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Registros recuperados: 6.548 | |
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Torres,Martha; Barrera,Junior. |
GCLASS is an algorithm which explores small samples of two distinct biological states for finding small sets of genes, which form a feature vector that is enough to separate these two states. A typical sample is a set of 60 microarrays, 30 for each biological state, with several thousand genes. The technique consists of the following: a spreading model defined in the space of small sets of genes studied and centered in each feature vector considered; the designing of optimal linear classifiers under this spreading model; and ranking the designed classifiers, based on their error and robustness relative to the spreading. The feature vectors used in the best classifiers are considered the best feature vectors. Due to the great number of potential feature... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gene expression; Classification; Parallel processing. |
Ano: 2004 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572004000400034 |
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Artigalás,Osvaldo; Paskulin,Giorgio; Riegel,Mariluce; Burin,Maira; Saraiva-Pereira,Maria Luiza; Maluf,Sharbel; Kiss,Andrea; Schwartz,Ida Vanessa D.. |
A 10-year-old speechless, mentally deficient male, with low arylsulfatase A (ARSA) activity, and presumably, methachromatic leukodystrophy, underwent genetic evaluation. As the clinical picture was not compatible with this diagnosisan ARSA gene and chromosome analysis were performed, showing the presence of a pseudodeficiency ARSA allele and a de novo apparently balanced t(16;22)(p11.2;q13) translocation. A deletion on the long arm of chromosome 22 encompassing the ARSA gene, as shown by FISH and array-CGH, indicated a 22q13 deletion syndrome. This case illustrates the importance of detailed cytogenetic investigation in patients presenting low arylsulfatase A activity and atypical/unspecific clinical features. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 22q13 deletion; Apparently balanced translocation; ARSA gene; Arylsulfatase A pseudodeficiency; Metachromatic leukodystrophy. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000300007 |
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MOURA, V. P. G.. |
Na regiao dos Cerrados, o comportamento de especies/procedencias de Eucalyptus e bastante variavel de acordo com as condicoes climaticas e edaficas do local do plantio e tambem de acordo com a origem do material genetico, com produtividade variando de 15 a 60 m3/ha/ano. E. pilularis tem melhor desempenho em cerrado de alta altitude (1000 m). Em altitudes mais baixas, este material apresenta problemas fitossanitarios e fisiologicos. E. grandis desenvolve-se melhor em chuvas. Procedencias de Atherton sao as mais indicadas; procedencias do sul da Australia, apesar de apresentarem as maiores taxas de crescimento ate os sete anos de idade, apos este periodo sao acometidas de disturbios fisiologicos, causando a morte de grande numero de plantas adultas. E.... |
Tipo: Capítulo em livro técnico (INFOTECA-E) |
Palavras-chave: Pines; Eucalypts; Cerrado; Eucalipto; Pesquisa; Pinheiro; Eucalyptus; Pinus; Research. |
Ano: 1997 |
URL: http://www.infoteca.cnptia.embrapa.br/infoteca/handle/doc/553462 |
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Hilsdorf,Silva; Oliveira,Claudio; Lima,Flávio César Thadeo de; Matsumoto,Cristianne Kayoko. |
The genus Brycon, the largest subunit of the Bryconinae, has 42 valid species distributed from southern Mexico to the La Plata River in Argentina. Henochilus is a monotypic genus, comprising a single species (H. wheatlandii) found in the upper Rio Doce basin. In the present study, partial sequences of the mitochondrial gene 16S were obtained for fifteen species of Brycon and for Henochilus wheatlandii. The results showed that the genus Brycon is paraphyletic, since Henochilus is the sister-group of B. ferox and B. insignis. The most basal species analyzed were the trans-Andean species B. henni, B. petrosus, and B. chagrensis. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Phylogeny; Molecular systematics; Mitochondrial DNA; Fish evolution; Systematic. |
Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572008000200034 |
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Yonggang,Liu; Sumei,Zhao; Hongbin,Pan; Shizheng,Gao. |
An investigation of differences in gene expression in the longissimus muscle of Meishan and Large White pigs was undertaken, using the mRNA display technique. A fragment of one differentially expressed gene was isolated and sequenced, whereupon the complete cDNA sequence was then obtained by using the rapid amplification of cDNA ends (RACE). The nucleotide sequence of the gene is not related to any known porcine gene. Sequence analysis revealed that the open reading frame of this gene encodes a protein with 322 amino acids, thus displaying high sequence identity with the PDZ binding kinase (PBK) of eleven other animal species - dog, horse, cattle, human, chimpanzee, crab-eating macaque, rhesus monkey, rat, mouse, gray short-tailed opossum and platypus, so... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Pig; PBK; MRNA differential display; RACE. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000400017 |
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Machado-Ferreira,Erik; Piesman,Joseph; Zeidner,Nordin S; Soares,Carlos A.G. |
As Rocky Mountain Spotted Fever is the most common tick-borne disease in South America, the presence of Rickettsia sp. in Amblyomma ticks is a possible indication of its endemicity in certain geographic regions. In the present work, bacterial DNA sequences related to Rickettsia amblyommii genes in A. dubitatum ticks, collected in the Brazilian state of Mato Grosso, were discovered. Simultaneously, Paracoccus sp. was detected in aproximately 77% of A. cajennense specimens collected in Rio de Janeiro, Brazil. This is the first report of Paracoccus sp. infection in a specific tick population, and raises the possibility of these bacteria being maintained and/or transmitted by ticks. Whether Paracoccus sp. represents another group of pathogenic Rhodobacteraceae... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Paracoccus; Rickettsia amblyommii; Amblyomma; Ixodidae ticks. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572012000500021 |
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Lima,Jamily L.R. de; Soares,Fabricio A.; Remedios,Ana C.S.; Thom,Gregory; Wirthlin,Morgan; Aleixo,Alexandre; Schneider,Maria Paula C.; Mello,Claudio V.; Schneider,Patricia N.. |
The memorization and production of song in songbirds share important parallels with the process of speech acquisition in humans. In songbirds, these processes are dependent on a group of specialized telencephalic nuclei known as the song system: HVC (used as a proper name), RA (robust nucleus of arcopallium), LMAN (lateral magnocellular nucleus of the nidopallium) and striatal Area X. A recent study suggested that the arcopallium of the Sayornis phoebe, a non vocal learner suboscine species, contains a nucleus with some properties similar to those of songbird RA, suggesting that the song system may have been present in the last common ancestor of these groups. Here we report morphological and gene expression evidence that a region with some properties... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Vocal learning; RGS4; Song nuclei; In situ hybridization. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572015000300249 |
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Benavides,M.V.; Damak,S.; Maher,A.P.. |
An Australian Merino flock was screened for low (resistant) and high (susceptible) yellow predictive colour (YPC) breeding values in order to compare extreme individuals using the differential display of mRNA technique. One differentially expressed cDNA band was visualised only in the resistant group. This band showed no identity with the DNA sequences of public databases; however, they showed short homologies with three database sequences related to transmembrane signalling functions. The use of these candidate genes as DNA markers needs to be confirmed against sheep with a wide range of susceptibility to wool yellowing to verify the results. |
Tipo: Info:eu-repo/semantics/article |
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Ano: 2000 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572000000200017 |
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Muniz,L.M.S.; Souza,L.A.; Barbosa,A.C.B.; Ambrosini,D.P.; Oliveira,A.P.; Carneiro,P.L.S.; Malhado,C.H.M.; Martins Filho,R.; Duarte,R.A.B.. |
Foram utilizados dados de pedigree de 2.558 bovinos da raça Gir Mocha nascidos no período de 1954 a 2005. As análises foram realizadas utilizando-se o programa Endog. Do total de animais estudados, 61,9%; 10,6% e 0,1% possuíam pedigree na primeira, segunda e terceira gerações, respectivamente.O número efetivo de rebanhos que forneceram machos reprodutores foi de 10,25 para pais e 3,87 para avôs, confirmando a baixa integralidade do pedigree. O número de animais fundadores foi de 975,5, e o número efetivo de fundadores de 141,34. O número de ancestrais na população referência foi de 924 animas, dos quais apenas 39 explicaram 50% da variabilidade genética da população.O coeficiente médio de relação foi estimado em 0,75%,... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ancestrais; Endogamia; Fundadores; Genealogia. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352012000600035 |
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Carneiro,Paulo Luiz Souza; Malhado,Carlos Henrique Mendes; Martins Filho,Raimundo; Carneiro,Antonio Policarpo Souza; Silva,Fabyano Fonseca e; Torres,Robledo de Almeida. |
Com o intuito de fornecer subsídios para programas de melhoramento, conservação e expansão da raça Indubrasil do Nordeste brasileiro, avaliaram-se o histórico evolutivo, as estimativas de parâmetros genéticos e a estrutura populacional da raça. Foram utilizadas informações do pedigree de animais nascidos no período de 1964 a 2006 e dados dos pesos ajustados aos 205, 365 e 550 dias de idade de bovinos nascidos a partir de 1976. As estimativas dos coeficientes de herdabilidade foram menores que as encontradas na literatura para os pesos ajustados nas três idades (P205: direta 0,11 ± 0,03 e materna 0,01 ± 0,03; P365: direta 0,16 ± 0,04 e P550: direta 0,15 ± 0,05) e os ganhos genéticos para as características decresceram no período avaliado (P205: -0,028... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Endogamia; Ganho genético; Intervalo de geração; Tamanho efetivo; Tendência genética. |
Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-35982009001200006 |
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Registros recuperados: 6.548 | |
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